The global next-generation sequencing market size is poised to reach USD 14.8 billion by 2030 with a CAGR of 12.4% from 2022 to 2030. The market totaled a valuation of USD 4.84 billion in 2021. The growth of the market is attributed to the growing research activities for developing test kits and vaccines. NSG refers to DNA sequencing methods that cater the genomic discovery. DNA and RNA sequencing, epigenetics, and examination of chromosomal abnormalities accumulate more data in global sequencing, and these are the factors responsible for the higher market share of NSG. Installation of NSG in clinical laboratories, testing, and disease diagnostics in the healthcare sector is creating opportunities for key players to focus on indulging investments in NSG solutions and R&D activities.
To attain an understanding of the linkage between genetics and disease, some countries have started investments in their mapping projects of their people. Additionally, governments across the globe are focusing on millions of genomes for research and intervention of options to test and cure cancer, complex disorders, and other yet-to-cure ailments. For instance, in Europe, France’s French Plan for Genomic Medicine 2025 initiative is undertaken by the EU to enhance the large-scale genomic data of the region.
The outbreak of COVID-19 had enforced various pharmaceutical and biotechnology companies to step forward to investigate and pen down research activities to develop vaccines and test kits. The substantial involvement in the COVID-19 vaccine development has created lucrative opportunities for the adoption of NSG solutions during the pandemic. For instance, during the pandemic, in China, MinION Mk1C a product by Oxford Nanopore Technologies (U.K.) for the sequencing of COVID-19 samples has been utilized by a group of researchers. Moreover, the technology of NSG for faster processing and rapid result time has been extensively utilized in clinical diagnostics. This, in turn, is poised for the market to witness growth in future years. For instance, Pediatrix Medical Group, GeneDx Inc., and OPKO, major companies operating in the market signed an agreement in August 2020 to offer state-of-the-art, next-generation gene-sequencing to improve clinical diagnosis in uncommon disorders for the newborn intensive care units.
Increasing technological advancement in NSG instruments and solutions is anticipated to fuel the market growth during the forecast period. For instance, Harvard University, DNA Script, and Broad Institute are contributing to collaborative research to develop technology for combining enzymatic DNA synthesis and NGS into a single instrument. Thus, the Intelligence Advanced Research Projects Activity in the U.S. granted USD 23 million to these institutes in January 2020.
Cost-effectiveness, rapid and accurate sample analysis, and technological advancements are the factors contributing to market growth. Additionally, genomics program development is increasing in almost all countries. Hence, the advent of NSG-based diagnoses along with government support will create a favorable environment for market expansion across the globe.
Next-Generation Sequencing Market Key Takeaways
- The oncology segment accounted for over 28.5% of the total market share in 2021. Rising prevalence of cancer warrants an emergence of technology that helps oncologists to better examine the mechanics of cancer and tumor cells making headway for the market to grow in future years
- The targeted sequencing and resequencing segment dominated the next generation sequencing market accounting for over 74.9% of the total market share. In order to analyze specific gene locations and isolated genetic expressions, a large amount of genome data is required. Hence, the demand for genome sequencing is increasing and companies are focusing on providing targeted sequencing services. Thereby, segment growth is expected to accelerate during the forecast period
- The academic research segment accounted for a revenue share of 52.9% in 2021 owing to the growing application of NSG solutions in the academic research projects held by the universities or research centers. Moreover, the provision of on-site bioinformatics courses including workshops on the practical implementation of NSG sequencing and data analysis is estimated to generate revenue through the academic research segment. Additionally, the NSG solutions Ph.D. projects are funded with scholarships in order to attain enhanced NSG products and services
- North America led the market accounting for over 49.2% of the total market revenue share in 2021. The presence of clinical laboratories that uses NSG to offer genetic testing services is expected to boost the market growth in the region. Moreover, the availability of technological advancements in the healthcare sector and continuous R&D investments by major companies are bolstering market growth in the region
Next-Generation Sequencing Market Segments
- Next-generation Sequencing Technology Outlook (Revenue, USD Million, 2018 - 2030)
- WGS
- Whole Exome Sequencing
- Targeted Sequencing & Resequencing
- Next-generation Sequencing Product Outlook (Revenue, USD Million, 2018 - 2030)
- Platforms
- Consumables
- Sample preparation
- Target Enrichment
- Others
- Next-generation Sequencing Application Outlook (Revenue, USD Million, 2018 - 2030)
- Oncology
- Diagnostics and Screening
- Oncology Screening
- Sporadic Cancer
- Inherited Cancer
- Companion Diagnostics
- Other Diagnostics
- Research Studies
- Clinical Investigation
- Infectious Diseases
- Inherited Diseases
- Idiopathic Diseases
- Non-communicable/Other Diseases
- Reproductive Health
- NIPT
- Aneuploidy
- Microdeletions
- PGT
- Newborn Genetic Screening
- Single Gene Analysis
- HLA Typing/Immune System Monitoring
- Metagenomics, Epidemiology & Drug Development
- Agrigenomics & Forensics
- Consumer Genomics
- Next-generation Sequencing Workflow Outlook (Revenue, USD Million, 2018 - 2030)
- Pre-sequencing
- NGS Library Preparation Kits
- Semi-automated Library Preparation
- Automated Library Preparation
- Clonal Amplification
- Sequencing
- NGS Data Analysis
- NGS Primary Data Analysis
- NGS Secondary Data Analysis
- NGS Tertiary Data Analysis
- Next-generation Sequencing End-use Outlook (Revenue, USD Million, 2018 - 2030)
- Academic Research
- Clinical Research
- Hospitals & Clinics
- Pharma & Biotech Entities
- Other Users
- Next-generation Sequencing Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
- Europe
- U.K.
- Germany
- Italy
- Spain
- France
- Asia Pacific
- Japan
- China
- India
- South Korea
- Australia
- Latin America
- Middle East & Africa
- South Africa
- Saudi Arabia
- List of key players of the Next-Generation Sequencing Market
- llumina
- F. Hoffman-La Roche Ltd.
- QIAGEN
- Thermo Fisher Scientific, Inc.
- Bio-Rad Laboratories, Inc.
- Oxford Nanopore Technologies
- PierianDx
- Genomatix GmbH
- DNASTAR, Inc.
- Perkin Elmer, Inc.
- Eurofins GATC Biotech GmbH
- BGI